Tests that examine the molecular features of a tumor, including mutations, gene expression, proteins, and biomarkers, to help identify potential treatment targets. Usually performed on biopsy or surgical tissue.
Tempus (US). Physician-ordered.
Caris Life Sciences (US). Physician-ordered.
Foundation Medicine (US). Accepts international patients. Physician-ordered.
Boston Gene (US). Also includes immune microenvironment analysis. Accepts international patients. Physician-ordered.
Noetik (US). Whole-exome sequencing, spatial profiling, and IHC with raw data returned to the patient. Collaborate with patients.
Valius Sciences (US). Maximalist diagnostics adding single-cell and proteomic profiling. Patient-orderable. Even One Ventures company.
Protean BioDiagnostics (US). Comprehensive precision oncology testing with patient consultation. Patient accessible, physician-ordered.
Belay Diagnostics (US). CSF-based genomic profiling for brain and spinal cord tumors, useful when tissue biopsy is risky or unavailable. Physician-ordered.
CNSide Diagnostics (US). CSF circulating tumor cell capture with molecular profiling for leptomeningeal disease, often detecting cases that conventional cytology misses. Physician-ordered.
RGCC International (Worldwide). Blood-based circulating tumor cell molecular profiling for treatment guidance. Patient or physician-ordered.
Navignostics (Switzerland). Spatial single-cell proteomic tumor analysis from a single FFPE section. Physician-ordered through early-access partner program.
BC Cancer Personalized Oncogenomics Program (Canada). Referral pathway in Canada.
CeGaT (Germany). Tumor-normal comparison with patient-specific neoantigen identification. Physician-ordered.
OncoDNA (Belgium). Physician-ordered.
Hartwig Medical Foundation (Netherlands). Referral through participating Dutch hospitals.
Vicinity Bio(Germany). Ultra-high-plex spatial proteomic tissue imaging with AI-driven pathology reports and biomarker-based therapy guidance. Physician-ordered.